TY - JOUR AU - Saha, Subrata AU - Mukherjee, Suman T1 - Response of the coelomocyte of Metaphire posthuma to chlorpyrifos toxicity JO - Journal of Stress Physiology & Biochemistry Y1 - 2025/march VL - 21 IS - 1 SP - 171 EP - 181 UR - http://www.jspb.ru/issues/2025/N1/JSPB_2025_1_171-181.pdf KW - Soil biodiversity KW - Earthworm health KW - Chlorpyrifos toxicity KW - Coelomocyte U1 - 1997-0838 N2 - Background: Chlorpyrifos, a widely used organophosphorus pesticide, poses significant environmental risks due to its persistence in soil and adverse effects on non-target organisms such as earthworms. This study investigates the toxicological impact of chlorpyrifos on the earthworm species Metaphire posthuma under controlled laboratory conditions. We assessed acute toxicity, growth rate, and immune responses, including coelomocyte viability. Earthworms were collected, maintained in a controlled environment, and exposed to varying concentrations of chlorpyrifos. Results: Results demonstrated a dose-response relationship, with higher concentrations of chlorpyrifos causing significant reductions in growth and coelomocyte viability. Additionally, immune function was notably compromised, highlighting the vulnerability of M. posthuma to chlorpyrifos exposure. Conclusion: These findings emphasize the importance of managing pesticide application rates to safeguard soil biodiversity and ecosystem health. The study underscores the need for stringent regulations and monitoring to mitigate the adverse effects of chlorpyrifos on crucial soil organisms like earthworms, which are vital for maintaining soil structure and fertility. ER -