TY  - JOUR
AU  - Shirur, Varsha
AU  - Dhone, Swati Kale
AU  - Shah, Shreyas
AU  - Sinha, Anamika
AU  - Sachdev, Sanpreet Singh
T1  - Role of copper in type 2 Diabetes Mellitus: A mini-review
JO  - Journal of Stress Physiology & Biochemistry
Y1  - 2024/august
VL  - 20
IS  - 3
SP  - 140
EP  - 145
UR  - http://www.jspb.ru/issues/2024/N3/JSPB_2024_3_140-145.pdf
KW  - Diabetes
KW  - Hyperglycemia
KW  - Metabolic disorders
KW  - Trace elements
KW  - Insulin resistance
U1  - 1997-0838
N2  - Diabetes Mellitus (DM) presents a significant global health challenge, with escalating prevalence rates and associated morbidity and mortality. Despite medical advancements, the mortality rates continue to rise, necessitating a deeper understanding of the pathophysiology and potential therapeutic targets. Copper, a vital trace element, plays an important role in various metabolic processes and homeostatic functions within the human body. Dysregulation of copper metabolism has been implicated in the pathogenesis and progression of DM, contributing to oxidative stress, insulin resistance, altered glycemic control, and metabolic abnormalities. The present review provides an illustrative overview of the role of copper in DM, elucidating its impact on oxidative stress, insulin resistance, glycemic control, and metabolic disturbances.
ER  -