ORIGINAL ARTICLE |
Methanolic (Meth) and ethanolic (Eth) Artemisia herba-alba Asso aerial parts extract including buds (AB), leaves (AL) and flowers (AF) were phytochemicaly analyzed using gas chromatography–mass spectrometry (GC/MS) analysis. A. herba-alba GC/MS chromatogram showed 16 and 39 compounds were occurred in Meth and Eth A. herba-alba AB extract, respectively, revealing that the Thujone (37.026% and 49.022%), 9-Octadecanamide, (Z)- (15.471% and 11.479%) and Eucalyptol (10.057% and 10.083%) were presented as a major compounds for Meth and Eth A. herba-alba AB extract, respectively. Whereas, 24 and 20 compounds were occurred in Meth and Eth A. herba-alba AL extract, respectively; where, 9-Octadecanamide, (Z)- (28.687%), Phytol (12.611%) and Palmitoleamide (12.304%) were presented as a major compounds for Meth A. herba-alba AL extract. Whereas, they were 9-Octadecanamide, (Z)- (25.687%), Dodecanamide (16.142%) and Camphor (14.494%) presented as a major compounds for Eth A. herba-alba AL extract. As for AF, 28 and 14 compounds were occurred in Meth and Eth A. herba-alba AF extract, respectively; where, 9-Octadecanamide, (Z)- (25.623%), Eucalyptol (11.879%) and Hexadecanamide (10.771%) were presented as a major compounds for Meth A. herba-alba AF extract. Whereas, they were 9-Octadecanamide, (Z)- (23.295%), Hexadecanamide (16.452%) and Thujone (13.144%) presented as a major compounds for Eth A. herba-alba AF extract. The current study highlights different bioactive compounds make this species as a good candidate to be used as a cheap natural source in pharmacology and medicine applications. The current study highlights for the first time A. herba-alba phytochemical analysis in Syria.
Key words: Artemisia herba-alba, gas chromatography–mass spectrometry (GC/MS), Phytochemical analysis, 9-Octadecanamide, (Z)-, Hexadecanamide