| ORIGINAL
ARTICLE |
|
|
|
The aim of this paper was to study
the effect of cold helium plasma on the parameters of oxidative
metabolism and crystallogenic activity of rat blood plasma.
Material and methods: The
experiment was performed on 20 male Wistar rats divided into control
(n=10, without manipulation) and main (n=10) groups. Animals of the
main group underwent a course, which included 10 daily procedures for
processing a pre-epilated area of the back skin (area – 10% of the body
surface) with a stream of helium cold plasma (duration – 1 min.). Upon
completion of the course, the intensity of lipid peroxidation, total
antioxidant activity, malon dialdehyde level and superoxide dismutase
activity were determined in the blood of all rats, and crystallogenic
properties were evaluated. The conjugation of potential shifts was
carried out by correlation analysis.
Results: It was found that cold
helium plasma transforms oxidative metabolism of blood plasma and its
crystallogenic properties, acting as an agent with moderate antioxidant
properties and a stimulant of dehydration structuring. In this case,
the antioxidant effect is realized, among other things, due to the
activation of superoxide dismutase.
