Secondary Metabolites Detected in Deep-Water Endemic Amphipods of Lake Baikal: Bacterial or Crustacean Origin?

Protasov, E.S.; Axenov-Gribanov, D.V.; Shatilina, Z.M.; Voytsekhovskaya, I.V.; Vereshchagina, K.P.; Lubyaga, Y.A.; Rzhechitskiy, Y.A.; Shirokova, Y.A.; Timofeyev, M.A.

Journal of Stress Physiology & Biochemistry, Vol. 13 No. 4 2017, pp. 104-109 ISSN 1997-0838
Original Text Copyright (cc) 2017 by Protasov, Axenov-Gribanov, Shatilina, Voytsekhovskaya, Vereshchagina, Lubyaga, Rzhechitskiy, Shirokova and Timofeyev

ORIGINAL ARTICLE

Secondary Metabolites Detected in Deep-Water Endemic Amphipods of Lake Baikal: Bacterial or Crustacean Origin?

Protasov E.S.¹, Axenov-Gribanov D.V.^1,2*, Shatilina Z.M.^1,2, Voytsekhovskaya I.V.¹, Vereshchagina K.P. ^1,2, Lubyaga Y.A.^1,2, Rzhechitskiy Y.A.¹, Shirokova Y.A.¹, Timofeyev M.A.¹

¹ Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
² Baikal Research Centre, Irkutsk, 21 Lenin str., Russia

*E-Mail: denis.axengri@gmail.com

Received October 29, 2017

The aim of the study was to conduct a dereplication analysis of crude extract of deepwater Baikal’s endemic amphipod species, Ommatogammarus albinus. Detected masses provide some evidence that amphipod’s extract might contain both host and microbiota secondary metabolites. Some of the masses correspond with known structures isolated from eubacteria. Also, two compounds did not match with any registered natural products from the database Dictionary of Natural Products. Those findings allow suggesting that Baikal’s endemics and their microbiota are promising sources of novel natural products.

Key words: Amphipods, Baikal, dereplication, natural products, secondary metabolites, Ommatogammarus albinus