Journal of Stress Physiology &
Biochemistry, Vol. 9 No. 4
2013, pp. 122-131 ISSN 1997-0838
Original Text Copyright (cc) 2013 by Dachanidze, Burjanadze,
Kuchukashvili, Menabde, Koshoridze
ORIGINAL ARTICLE
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QueryDate : 2016-12-24
Cites : 2
Functioning of the Antioxidant
System under Psycho-Emotional Stress
Natalia Dachanidze*, George
Burjanadze, Zurab Kuchukashvili, Ketevan Menabde, Nana Koshoridze
Department of Biology, Faculty of Exact
and Natural Sciences, I. Javakhishvili Tbilisi State University,
Tbilisi 0128, Georgia
*E-Mail: n.dachanidze@yahoo.com
Received June 20, 2013
It was studied intensity of lipid
peroxidation and activity of enzymes from antioxidant system in blood
plasma and cardiac muscle cells among laboratory rats under 40 days of
isolation and violation of diurnal cycle. The
received data show that at the
background of quantitative changes in NO there also take
place changes in the intensity of lipid peroxidation process,
indicated by quantitative change in
the concentration of Malone dialdehyde
and diene conjugates, including Malonedialdehyde and marked with
a reduced activity of antioxidant system enzymes, such as catalase and
superoxide dismutase activity. Based on the results, we proposed that
psychological stress is one of the factors contributing to the
development of various cardiac diseases.