Journal of Stress Physiology &
Biochemistry, Vol.
8 No. 4
2012, pp. 72-77 ISSN 1997-0838
Original Text Copyright (cc) 2012 by Kataria, Kataria
ORIGINAL
ARTICLE
Data source : Google Scholar
QueryDate : 2016-12-24
Cites : 7
Evaluation of Oxidative Stress
in Sheep Affected with Peste des petits ruminants
Kataria A. K.*1, Kataria
N.2
1
Apex Centre for Animal Disease Investigation, Monitoring and
Surveillance, College of Veterinary and Animal Science, Rajasthan
University of Veterinary and Animal Sciences, Bikaner – 334 001,
Rajasthan, India. 2 Department of Veterinary Physiology, College of Veterinary
and Animal Science, Rajasthan University of Veterinary and Animal
Sciences, Bikaner- 334 001, Rajasthan, India.
The aim of the investigation was to
evaluate oxidative stress in sheep affected with peste des petits
ruminants (PPR). Oxidative stress in the affected sheep was evaluated
by determining various serum biomarkers viz. vitamin A, vitamin C,
vitamin E, glutathione, catalase, superoxide dismutase, glutathione
reductase and xanthine oxidase, the mean values of which were
1.70±0.07µmol L-1, 13.00± 0.10 µmol L-1, 2.25 ±0.07 µmol L-1, 3.10
±0.06 µmol L-1, 140.00 ±8.00 kU L-1, 294.22 ±9.91 kU L-1, 6.99± 0.05 kU L-1 and 100.10 ±3.00 m U L-1, respectively. The levels of vitamins A,
C, E and glutathione decreased significantly (p≤0.05) and the serum
catalase, superoxide dismutase, glutathione reductase and xanthine
oxidase activities increased significantly (p≤0.05) in affected sheep
as compared to that in healthy ones. On the basis of the altered levels
of serum biomarkers of oxidative stress it was concluded that the
animals affected with PPR developed oxidative stress. The findings
suggested the relevance of periodic assessment of oxidative status in
ruminants for healthier management through supplementation of proper
antioxidants as supportive treatment in PPR and in healthy in-contact
animals.
