Journal of Stress Physiology & Biochemistry, Vol. 3 No. 1,
2007, pp. 18-24.
Original Text Copyright (cc) 2007 by Kosmachevskaya, Shumaev,
Arredondo-Peter, Topunov
ORIGINAL
ARTICLE
Data source : Google Scholar
QueryDate : 2016-12-24
Cites : 6
INFLUENCE OF TERT-BUTYL
HYDROPEROXIDE AND
NITROSOGLUTATHIONE ON Escherichia
coli CELLS EXPRESSING LEGHEMOGLOBIN
Kosmachevskaya1 O.V., Shumaev1 K.B.,
Arredondo-Peter2 R., Topunov1 A.F.
1A.N. Bach Institute
of
Biochemistry, Russian Academy of Sciences, Moscow 119071, Russia 2Lab. de Biofisica y
Biologia Molecular, Universidad Autonoma del Estado de Morelos,
Cuernavaca 62210, Mexico e-mail: topunov@inbi.ras.ru
Received April 3, 2007
Abstract - Influence of expressed
leghemoglobin on stability of Escherichia coli
cells to reactive oxygen and nitrogen species – tert-butyl
hydroperoxide and S-nitrosoglutathione was studied. We determined both
action of these compounds on cells with different level of
leghemoglobin expression and peroxidase activity of the cells. It was
shown that priority of pro- or antioxidant properties of leghemoglobin
is dependent on its concentration in the cells. In cells with reduced
synthesis leghemoglobin mostly functions as prooxidant, in cells with
intensive one – as antioxidant.
